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David Hyde Pierce - Wikipedia

David Hyde Pierce on a Decade of ‘Frasier’ Memories

[Air Date: September 23, 2003] Join Ellen in an interview with David Hyde Pierce from the iconic series “Frasier.” They dive into...

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David Hyde Pierce says that his absence from the Frasier reboot wasn't due to hard feelings — but a busy schedule and a new story to tell that made him decide to pass on the Paramount+ reboot.
Luckily, David Hyde Pierce said, Kelsey Grammer was a complete team player who cared just as much about his co-stars as he did about his own performance on Frasier, which ran for 11 seasons on NBC from 1993-2004. “Kelsey Grammer is one of the finest actors I've ever worked with,” Pierce enthused.
Niles Crane (born 1957) is a fictional character on the American sitcom Frasier, a spin-off of the television show Cheers. He was portrayed by David Hyde Pierce. Niles is the younger brother of Frasier Crane (played by Kelsey Grammer).
John Lithgow. John Lithgow turned down Frasier Crane role during 'snobbish' phrase.);})();(function(){window.jsl.dh(9bLFZrahFOXYwPAPj9qcyQg__194,
As for why Niles isn't in the Frasier reboot, it stemmed from David not wanting to return to the role after almost two decades after the final episode. Kelsey confirmed this to People in November 2022, stating how David's choice to not come back actually opened up for new storylines to emerge.